This is a very long (and complex*) thread and I'm interested in this device. I would like to know if it would playback the synthesized speech without interrupting/pausing/stopping the gameplay (like what happens with other games) on a stock CPC 464? Or is just too much for a stock CPC just like when voices are digitized?
Digitized playback?
Hi! And thanks for asking.

The LS3 has an 128 KB EEPROM, which can be programmed from the CPC. After you have programmed it once (takes very few seconds only), you can use it to play samples again and again. You can program 512 byte pages. So it's possible to play different samples / sounds or whatever. It's really cool for games! The RSX ROM does support this feature. But from the machine code side (or use even BASIC!) it's very simple too. Example code can be requested by Email or PM.
If this is possible - are there any examples out there?
Yes, IIRC LambdaMikel has some example Discs (see his project page).
EDIT: If you "just" want to let the device speak text, then you send the sentence to the device and it will speak it without interruption of the CPC.
Sorry, I'm not sure if I got it.